Idiopathic inflammatory myopathy: From muscle biopsy to serology
نویسندگان
چکیده
منابع مشابه
بررسی ارزشمند بودن بیوپسی عضلانی به روش بسته با سوزن در تشخیص بیماریهای التهابی عضله
ABSTRACT To determine the usefulness of a method of percutaneous needle muscle biopsy in patients with suspected idiopathic inflammatory Myopathy. The yield of percutaneous needle muscle biopsy was studied in 15 patients during 1997-2000 who were hospitalized in Hazrat Rasool Akram hospital. A diagnosis of idiopathic inflammatory myopathy was confirmed histopathologically in 8 patients...
متن کاملApproach to Diagnosis and Management of an Idiopathic Inflammatory Myopathy
Idiopathic inflammatory myopathies are a group of autoimmune diseases characterized by proximal muscle weakness and inflammation of skeletal muscle. Specific forms of idiopathic inflammatory myopathy include polymyositis, dermatomyositis, and inclusion body myositis. Inflammatory myopathies have a bimodal distribution, occurring in patients between 10 and 15 years and 45 and 60 years of age, ex...
متن کاملMuscle Biopsy
Muscle biopsy has been used for a long time for diagnosis of muscular, nerurogenic and systemic disorders with muscle involvement, because only very few of these disorders show sufficient specific clinical features for definite diagnosis. Since the presence of difficulties in the screening of numerous genes, muscle biopsy could be a time and cost effective procedure for solving the diagnostic p...
متن کاملEnhanced autoantigen expression in regenerating muscle cells in idiopathic inflammatory myopathy
Unique autoantibody specificities are strongly associated with distinct clinical phenotypes, making autoantibodies useful for diagnosis and prognosis. To investigate the mechanisms underlying this striking association, we examined autoantigen expression in normal muscle and in muscle from patients with autoimmune myositis. Although myositis autoantigens are expressed at very low levels in contr...
متن کاملRespiratory chain enzyme defects in patients with idiopathic inflammatory myopathy.
OBJECTIVE To analyse muscle respiratory chain enzymes in idiopathic inflammatory myopathy. METHODS Four consecutive female patients seen at our hospital with idiopathic inflammatory myopathy were studied. Muscle histochemical staining included NADH tetrazolium reductase and succinate dehydrogenase tests. Activity of rotenone sensitive NADH cytochrome c reductase (complex I and III) succinate ...
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ژورنال
عنوان ژورنال: Indian Journal of Rheumatology
سال: 2020
ISSN: 0973-3698
DOI: 10.4103/injr.injr_165_20